Effect of cyclosporin A on immunological response in lungs of guinea pigs infected with Trichinella spiralis.

The Transmission of the Virus of Lymphocytic Choriomeningitis by Trichinella Spiralis

In experiments in which guinea pigs were infected concurrently with the virus of lymphocytic choriomeningitis and the parasitic nematode, Trichinella spiralis, proof was obtained that trichinella larvae, after maturation in the muscles, had acquired the virus and were capable of transmitting it to new susceptible hosts. Transmission resulted both when living larvae were fed to normal guinea pig...

Evaluation of Humoral Immune Response to Foot-and-Mouth Disease Vaccination in Experimentally Infected Guinea Pigs with Trypanosoma evansi

Reactivity and specificity of Trichinella spiralis fractions in cutaneous and serological tests.

Six diethylaminoethyl-cellulose fractions of a larval Trichinella spiralis extract, an Ascaris suum extract, and a nonrelated protein were used for cutaneous tests in guinea pigs with 8-, 14-, and 73-day-old T. spiralis infections, in guinea pigs with 13-day-old A. suum infections, and in normal guinea pigs. A selected T. spiralis fraction was used in hemagglutination (HA) tests with sera of 8 ...

Amelioration of Myogenin, Bcl-2 expression and DNA damages in myocytes of Trichinella spiralis-infected mice after immunization with gamma radiation-attenuated larvae

Background: In trichinosis, the presence of muscle larvae inside skeletal striated muscle causes loss of identity and function of myotube through the releasing of myogenin and myosin. Considering the dominant role of vaccination, research on gamma radiation-attenuated vaccine has very promising value. The goal of this study was to determine the efficacy of vaccination with radiation-attenuated ...

Comparison of IgM, IgG1 and IgG2 responses to Trichinella spiralis and Trichinella britovi in swine.

Pigs infected with T. spiralis and T. britovi were followed by double (IgG) and triple antibody ELISA (IgG1, IgG2 and IgM) during a 12-week-period. Specific IgG and IgG1 responses were similar and showed a significant relation with the infecting doses and intensity of infection. Response to T. britovi was slightly lower than in groups infected with the same dose of T. spiralis. IgG2 response wa...